The Fight Against COVID-19
Coronaviruses (CoV) are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV).
Coronavirus disease (COVID-19) is a new strain that was discovered in 2019 and has not been previously identified in humans.
Coronaviruses are zoonotic, meaning they are transmitted between animals and people. Detailed investigations found that SARS-CoV was transmitted from civet cats to humans and MERS-CoV from dromedary camels to humans. Several known coronaviruses are circulating in animals that have not yet infected humans.
Common signs of infection include respiratory symptoms, fever, cough, shortness of breath and breathing difficulties. In more severe cases, infection can cause pneumonia, severe acute respiratory syndrome, kidney failure and even death.
China’s Response to the Epidemic
Two make-shift Hospitals & Stadium Renovated Hospital
Mindray’s Fight Against COVID-19
Donated Over 4.71 Million USD Worth of Medical Device
Mindray Ventilator SV300 on the Frontline Against COVID-19
Thousands of Newly Installed SV300 in Wuhan & Surrounding Areas
COVID-19 Clinical Challenges
Patient Care
Patient Care: Comprehensive Therapy
Standard respiratory therapies management for the patients with ARDS, which mainly include high-flow oxygen therapy (HFOT), non-invasive ventilation (NIV) and invasive ventilation(IV).
Patient Care: Comprehensive Modes & Tool
Management of Hypoxemic Resp. Failure & ARDS
• Implement mechanical ventilation using lower tidal volumes (4–8 ml/kg predicted body weight, PBW) and lower inspiratory pressures (plateau pressure <30 cmH2O).
• PEEP titration requires consideration of benefits (reducing atelectrauma and improving alveolar recruitment) vs. risks (endinspiratory overdistension leading to lung injury and higher pulmonary vascular resistance).
Patient Care: Weaning Assessments
P0.1 Clinical application: P0.1 ≈ -3 ~ -5 cmH2O
NIF Clinical application: NIF < -30 cmH2O
RSBI Clinical application: RSBI < 105
SBT Clinical application: 30 min – 120 min trial
Infection Control
Infection Control: Autoclavale Valves
Components which can be Autoclavable:
- Inspiration safety valve assembly
- Expiration valve assembly (include the membrane)
Infection Control: HEPA Filters
Maintenance Schedule
- HEPA: Annually, or every 5000 hours, or as necessary
- Turbine: Every 20,000 hours
Ease of Use
Ease of Use: Adaptation to Demanding Environment
Due to high demands in COVID-19 patients, departments cannot simultaneously provide adequate gas supply
Ease of Use: AMV Mode
- Sets a target percent of minute ventilation(%MV) based on the IBW
- Sets PEEP, FiO2
Ease of Use: User Interface – SV300
- Tab Layout Structur
- Color-sorted Values
- Alarm Range Indicator
- Up to 4 Waveforms & 2 Loops
- Visual-guided Self-test
- Parameter Prompt
Ease of Use: Alarm Management
- Alarm priorities
- Graphical Alarm Guideline
- Alarm reasons & troubleshoot suggestions
- Link to alarm setting window or machine status window
”“With SV300 we are able to quickly support different stages of respiratory failure with different respiratory support technologies from HFOT, noninvasive ventilation, to invasive ventilation. The turbine design on Mindray SV300 allows it to work independently without air gas source or compressor while preventing cross-infections with the HEPA filter. Therefore, it is commonly selected by many wards or hospitals without high-pressure air source to treat critically ill patients with COVID-19.”
Jingen Xia,Respiratory Therapist, Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China